Trust me on going with radiant heat, ITS almost like CRACK - with out all the horrible side affect.
Once you have radiant you will not know how you lived with out it. No more cold tile floor, for the wife to complain about when running to the bathroom in the middle of the night.
In regards to how to hook up system, may want to scope out the Central Boiler website - they have soem pretty good illistrations on how to hook up different application, even mulitboiler.
Also, you can get away with not having a back up; heat source, pump, fill in the blank. Just remember MURPHY's LAW - everythign seems to break just after close on the coldest day, darkest night ....
I woudl never install a heating system with only one heat source, yes new equipment is less likely to break, but it does not mean it WON'T.
Have you started looking into what your BTU load will be for your set up??? Cause your OWB, might need to be a BEAST (If memory serves, garage = 120' x 60' = 7200sf) + SnowMelt + DHW + Hot Tub + Pool = ALOT of BTU's I feel