I run four of the Grundfos Alphas (three in my house radiant plumbing and one at my OWB). The ones in the house are all set to AutoAdapt and run at various speeds, from 2gpm to 7gpm. I have eight runs of 1/2" pex in the floor on the first floor and eight runs in the second floor with each run being 128' each. I replaced the original Taco pumps because they were using too much electricity, since I am off grid solar. The Grundfos pumps use less than 1/3 of the of the original Taco pumps combined.
I have set the pump on the OWB at the highest constant pressure and it runs at 38-40 watts and 4-5gpm. My OWB pumps runs year round, and during the summer when my boiler is shut down, I turn it to AutoAdapt and just let it run.
I hope that helps some. For me, being off grid solar, it's the only way to go.