I wouldn't worry about mice ect in the insulation if you will be burning it in the colder parts of the year. No mouse is going to last snuggled up to a 180 degree water jacket.
I only recommend glycol if there is a high chance of freezing. In other words only if you will be allowing the furnace to be out a lot when it is below freezing. Glycol doesn't transfer heat as well as water and will degrade over time. If you let the furnace go out when its just below freezing the running pump will keep it from freezing up.
The plumbing on a boiler hookup is very simple and most homeowners could do it themselves. The wiring is a little more tricky, there are several ways to do it depending on how your gas boiler is set up. You want to be sure both systems can work and switch back and forth automatically. Do you have multiple zones and does your gas boiler maintain heat 24/7 or is it on demand?