jerkash for what it is worth i use a header system. feed and return. my hot water from teh OWB comes into the house to a 1 inch header with outlets on it for the furnace, the domestic water eschanger, floor heat, rads in teh basement and a rad in my fireplace as well (no more fire in the house) these "outlets" all have a ball valve on them and they all from the feed header to the "appliance" then back to a return header that are also vlaved. this way all "appliances" are recieving the same temp water and each "appliance" if there is a problem can be isolated and taken off stream for repairs without haveing to shut down the entire system.
if you are going to run from one 'appliance' to another may i suggest you put a by pass line at each one so you can take one off line if needed.
here is another belief of mine (and maybe not any one else) but if you put 180 degree water through your domestic exchanger the OWB water leaving that exchanger (when you are using domestic water) may have a temp as low as 160 and if that water goes to another appliance it may leave that appliance at only 140 and so on...you can see if you are using multiple "appliance" you could eventually be getting too cold of water to do any good.
another andvantage i see in the header system is you can add 'appliances" easily as you require them.
perhaps if you add too many you will require a booster pump but so far i have 5 lines running from my header and 1 pump does everything except i have a small pump on my infloor loop to circulate teh water in the floor
good luck with your project