jDruhnke,
Here is my setup and about what I run for GPM;
Main house (3500sf - All in slab, or heat emission plates, and a side arm), no more that 200' round trip of 1-1/4" PEX, with a SS Alpha running between 5-8 gpm depending on which setting
Detached garage (4000sf - ALL IN SLAB), no more than 125' round trip of 1" PEX,with a SS Alpha running between 3-5 gpm depending on which setting
I have FPHE in both building and heating them has never been an issue, once I found a couple of gremlins (STUPID CHECK VALVE, and a little faulty wiring

on thermostats)
...also I tend to stay away from 26-99's just because of the large power draw. I know they have there applications, and I do have one installed as part of a Snowmelt loop I have installed (haven't turned it on yet, too afraid I will have to stand at boiler and THROW wood in all the time

)