thermo pex says you can push water through their 1.25 inch pex at 6.6 feet per second =17 gpm anything after this flow starts to erode fittings prematurely
pex charts put the flow rate at 4 feet per second = 11gpm
your 4 floor loops (5/8 pex) will require between 2 and 3 gpm for each loop for a total of 8 to 12 gpm when calling for heat. if you wish to use a modine and a plate exchanger at the same time you will require a pump that can deliver close to 15 gpm likely (or as suggested, 2 pumps)
you could use a header system and put the modine on line with your plate exchanger. you could let the plate exchanger run all the time (to complete your loop to and from teh boiler) you could also if you wish not to put water through your modine, use a zone valve on a thermostat, and a zone valve and pump on a thermostat for your floor heat
just suggestions there are likley a few other ways as well
along with any system design you choose, you will need to factor in your head loss for that system
remember as you increase the velocity you will also increase the friction in the pipe